Lorena BenedettiDivision of Cancer Studies
King's College London, The Francis Crick Institute
- Hear how genome analysis identified mutation in all member of the cohesion complex and tumour suppressor cells, making them valuable candidates for development of targeted cancer therapy
- Learn how different combinations of siRNAs and CRISPR knock out assays can be used to evaluate the synthetic lethal interaction between STAG1 and STAG2.
- Explore how STAG1 may be an effective candidate for the development of targeted therapy for tumors harboring STAG2 loss of function mutations.