17 - 18 May, 2017 | London, UK

Lorena Benedetti


Division of Cancer Studies
King's College London, The Francis Crick Institute


12:35 PM Synthetic lethal interaction between the tumour suppressor STAG2 and its paralog STAG1

  • Hear how genome analysis identified mutation in all member of the cohesion complex and tumour suppressor cells, making them valuable candidates for development of targeted cancer therapy
  • Learn how different combinations of siRNAs and CRISPR knock out assays can be used to evaluate the synthetic lethal interaction between STAG1 and STAG2.
  • Explore how STAG1 may be an effective candidate for the development of targeted therapy for tumors harboring STAG2 loss of function mutations.


Check out the incredible speaker line-up to see who will be joining Lorena .

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